A searchable database is now ready to help study Alzheimer’s disease.
Neuroscience and biomedical informatics researchers at The Ohio State University Wexner Medical Center and College of Medicine created the comprehensive, user-friendly repository.
The free database – known as ssREAD – is outlined in a manuscript published online in Nature Communications.
This database will help study the pathology of Alzheimer’s disease.
The database encompasses 277 integrated datasets from 67 Alzheimer’s disease-related scRNA-seq & snRNA-seq studies, totaling 7,332,202 cells. The repository also includes 381 spatial transcriptomics samples from 85 human and mouse studies.
- Detailed annotations including cell types and spatial layers
- Differential gene expressions and functional enrichment analysis
- Spatially variable genes and deconvolution with single-cell datasets
User-friendly web server to provide comprehensive analysis interpretations and filters support multiple selections
- Scatter plots for clusters, cell types, and spatial layers
- Feature plots and violin plots for gene expression profile
- Real-time gene set enrichment analysis
The Ohio State University release
