In a recent study, a Johns Hopkins Medicine researcher and collaborators analyzed data on adults to determine if there is a link between having a heart attack and cognitive decline.
The new findings, published May 30 in JAMA Neurology showed that having a heart attack, among those who had never had one before, was not associated with a sudden decline in cognition. But, for those who had a heart attack versus those who did not, there was a significantly faster decline in cognition over the years following the heart attack. The decline in global cognition after a heart attack was equivalent to about six to 13 years of cognitive aging.
In a pooled analysis of six different large studies of adults between 1971 and 2019, researchers determined whether people who have had heart attacks showed changes in cognition compared with people similar to them in all respects except they had not had a heart attack. The researchers used a point system to measure participants’ global or overall cognition over time, as well as memory and executive functioning — or how well people make complex cognitive decisions.
For those who suffered a heart attack, while the researchers did not find significant cognitive decline immediately after their first heart attack, the participants’ cognitive tests showed a decline over the years following the event. The scores on several different cognitive tests were combined to represent one cognitive domain. A decrease in points indicated a decline in that cognitive domain.
The study sample comprised 30,465 people who had not experienced a heart attack or stroke and did not have dementia at the time of the first cognitive assessment; 29% of the individuals were Black, 8% were Hispanic and 56% were women. Of the overall sample, 1,033 individuals went on to have at least one heart attack, and out of that, 137 had two heart attacks. Individuals who experienced heart attacks were more likely to be older and male.
