Johns Hopkins rewrites obsolete blood-ordering rules

May 30, 2013

Johns Hopkins researchers have developed new guidelines—the first in more than 35 years—to govern the amount of blood ordered for surgical patients. The recommendations, based on a lengthy study of blood use at The Johns Hopkins Hospital (JHH), can potentially save the medical center more than $200,000 a year and improve patient safety, researchers say.

A report on the research that led up to the new guidelines, published online in the journal Anesthesiology, suggests millions of dollars a year nationwide could be saved in laboratory costs and wasted blood if other hospitals also reconsider how they prepare blood for surgery.

The researchers say the guidelines ensure that blood is readied for surgeries likely to require transfusions and that time isn’t spent preparing blood for surgeries that rarely require them.

Study leader Steven M. Frank, MD, and his colleagues analyzed computerized anesthesia records—including blood use—for 53,000 surgeries performed at JHH from January 2010 through March 2012. They looked at how often blood transfusions were needed during various types of surgeries, and how much blood was transfused. Then they devised a new mathematical formula to determine whether patients undergoing each type of surgery would most likely not need blood, which ones might possibly need blood (for which a sample was sent to the lab to get the patient’s blood type and other information), or whether blood was very likely to be needed.

In cases where the algorithm “guessed wrong,” Frank notes, emergency blood (type O-negative) can be procured within minutes with minimal risk of reaction. That scenario occurred in three of every 1,000 cases, he says, but those patients had substantial anemia prior to surgery, a condition for which blood should be ordered anyway. Read the article.