QIAGEN announced it has entered into a collaboration with Eli Lilly and Company to support the development of a QIAstat-Dx in-vitro diagnostic (IVD) to detect APOE genotypes which can play a role in the diagnosis of Alzheimer’s disease.
The panel will be integrated with QIAGEN's multiplex testing platform QIAstat-Dx. The QIAstat‑Dx system, designed for laboratory use, employs cost-efficient, single-use cartridges with built‑in sample processing and on-board reagents. Utilizing multiplex real-time PCR, it reliably detects genetic variants, with results in about an hour.
The QIAstat-Dx IVD panel will detect all APOE genotypes (APOE2, APOE3, APOE4). They can play a role in the diagnosis of patients with Alzheimer's disease, which is the most common cause of dementia. People carrying the APOE4 genotype have a higher risk of developing Alzheimer's and are likely to do so earlier in life compared to others. Those who carry two copies of this genotype (homozygous) are most likely to develop clinical symptoms of the disease.
