Diagnostics

PNA FISH test with rapid results

The EK/P aeruginosa PNA FISH diagnostic test identifies Escherichia coli and/or Klebsiella pneumoniae as well as Pseudomonas aeruginosa directly from positive blood cultures. PNA FISH tests now provide rapid, therapy-guiding results for 95% to 99% of patients with bloodstream infections and positive blood cultures. EK/P aeruginosa PNA FISH will enable microbiology labs to provide clinicians rapid, accurate, Gram-negative pathogen identification results in hours instead of days. This test can provide critical results 24 to 48 hours sooner than conventional methods to help clinicians improve care and outcomes for patients with Gram-negative bloodstream infections.

AdvanDX

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Open system for nucleic-acid testing

Jaguar offers laboratories a cost-effective, rapid solution for nucleic-acid testing. It is an open system, enabling automation of manual laboratory-developed tests resulting in a virtually unlimited menu. This flexibility will help prevent obsolescence and the need to replace equipment as new tests are requested by clinicians. With the ability to process samples 24/7 in random-access mode, Jaguar is capable of processing raw patient samples, such as swabs, urine, plasma, cerebrospinal fluid, and blood, with results available in 45 to 90 minutes. The system’s unitized reagent strips and microfluidic cartridge reduce the risk of amplified nucleic-acid contamination.

HandyLab

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Fecal parasite test features improved methodology

PARATEST is an alternative to traditional fecal examination, making the process much easier and secure, avoiding steps in order to recognize the fecal parasites. PARATEST it is a prefilled container used for filtering, concentrating, and recovering parasites from fixed/preserved body waste. The filtration device utilizes a 266-µ polyester mesh and a cone-shaped opening to maximize the filtration areas. When a fixed/preserved specimen is filtered through the device, the larger fecal matter is separated from the preserved fecal specimen. This traps the fecal matter, allowing parasite forms to pass through the device onto a glass microscope plate.

DK Diagnostics

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Antibodies for specific diagnosis of breast cancer

A comprehensive panel of antibodies for breast carcinoma includes ADH-5 (atypical ductal hyperplasia). ADH-5 is an antibody cocktail composed of CK5/CK14 + p63 + CK7/CK18 antibodies and can solve multiple clinical problems. The antibody panel allows for prognostic, predictive, and diagnostic tests specific for breast carcinoma. These markers are available as single primary antibodies, cocktailed, or a multiplex combination, and are available for clinical applications. ADH-5 can solve multiple clinical problems including 1) differentiating hyperplasia of the usual type from atypical ductal hyperplasia, 2) identifying microinvasion and invasive ductal carcinoma, and 3) distinguishing basal phenotypes on triple negatives.

Biocare Medical

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Monitor celiac-disease activity

Measurement of antibodies to gliandin is useful in monitoring celiac-disease activity and compliance to a gluten-free diet. Conventional ELISA methods use crude gliadin antigen and have shown limited sensitivity and specificity; the BINDAZYME Human Anti-Gliadin MPG IgG and IgA EIA Kits use a modified gliadin peptide with high sensitivity and specificity. In the small intestine, ingested gluten is broken down into gliandin peptides which are deamidated by the enzyme tissue tranglutaminase or tTg. These peptides enhance the immunogenicity of gliandin, demonstrating improved diagnostic accuracy. Gliadin antibodies are produced early in the disease and are helpful in early detection.

Binding Site

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Precise profiling

RanplexCRC is a diagnostic test that can detect 28 polymorphisms associated with colorectal cancer in a single stool sample. It does not require a hospital visit or dietary restrictions; has great sensitivity; and may more accurately profile patients and, thus, reduce the number of patients for colonoscopy — saving time, resources, and reducing patient discomfort. RanplexCRC can simultaneously detect 28 mutations from four key genes in cancer or pre-cancerous cells. Selected mutations present in APC, KRAS, BRAF, and Tp53, along with wild-type control sequences, are represented on two biochips detected using the biochip array analyzers by this company.

Randox Laboratories

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Differentiates flus A and B

The OSOM Influenza A & B Test differentiates between the two. The product is easy to read, uses nasal-swab specimens, and includes two extra test sticks for external quality-control (QC) testing. Test uses less than one minute of hands-on time, and results are ready in 10 minutes. The test can be stored at room temperature and has a shelf life of 12 months from date of manufacture; specimens may be held at room temperature for up to eight hours or refrigerated for up to 24 hours. Extracted samples may be held at room temperature for up to 24 hours.

Genzyme Diagnostics

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